Eased MPFC activity (Zaki et al., 2009). MPFC is also consistently activated in mentalizing or theory of mind tasks in which participants infer the mental states of other people (Frith and Frith, 2006). In addition, empathy for social and emotional pain activates both MPFC and DMPFC (Masten et al., 2011; Bruneau et al., 2012; Meyer et al., 2012). For sufferers with neurodegenerative disease, atrop